The NAD+-mediated self-inhibition mechanism of pro-neurodegenerative SARM1
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Last updated 20 Juni 2024
Neurotoxins subvert the allosteric activation mechanism of SARM1 to induce neuronal loss
The curious case of SARM1: Dr. Jekyll and Mr. Hyde in cell death and immunity? - Sarkar - 2023 - The FEBS Journal - Wiley Online Library
Base-Exchange Enabling the Visualization of SARM1 Activities in Sciatic Nerve-Injured Mice
Structural basis for SARM1 inhibition and activation under energetic stress
Constitutively active SARM1 variants that induce neuropathy are enriched in ALS patients, Molecular Neurodegeneration
A phase transition enhances the catalytic activity of SARM1, an NAD+ glycohydrolase involved in neurodegeneration
The addition of NR blocks NaR-mediated axonal protection. A) Time
Neurotoxins subvert the allosteric activation mechanism of SARM1 to induce neuronal loss
SARM1 activation and its downstream pathways are distinct in neuronal compartments
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